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Elavil Withdrawal

If you wish to remain on Elavil but eliminate current Elavil withdrawal side effects, click here.

If you want to taper off the Elavil and you are not sure where to start, you can click here and read the bestselling book, How to Get Off Psychoactive Drugs Safely or send Jim Harper an email at Jim@theroadback.org and he will guide you through the process of Elavil withdrawal.

If you are experiencing brain zaps, electrical jolts in the head, click here

Elavil withdrawal - "I know Elavil isn't prescribed often these days, but my doctor did. I had tried often to withdrawal off Elavil without success. Your approach made this ease." Peter

The F.D.A. estimates 10% of the people withdrawing off an antidepressant will not be able to succeed due to withdrawal side effects. Elavil is not different. If you are one of the lucky 90% that can do a successful Elavil withdrawal you still need to rebuild your body once off Elavil. This site provides information what to do for Elavil withdrawal and after Elavil withdrawal if you were able to succeed on your own.

Let’s take at how to have a successful Elavil withdrawal first.

There are two parts that make a successful Elavil withdrawal possible. How you reduce the Elavil during withdrawal and taking a few supplements that will help eliminate any Elavil withdrawal side effects. It does not matter what dosage of Elavil you are taking or how long you have used Elavil; the reduction of Elavil is the same. You want to reduce Elavil by no more than 10% and only reduce by an additional 10% every 2 weeks. This is the safest and most successful way to become Elavil free and not suffer during withdrawal.

Check with your pharmacist for compounding the Elavil and the best option. The next best method is to use a pill slicer and a milligram scale. Get a 7-day pill holder and once a week cut your pills for the coming week. Roughly 90% of you will be able to complete an Elavil withdrawal using the method above. However, you will most likely experience flu like symptoms, headache, brain zaps, anxiety, and insomnia or in some cases extreme fatigue. These symptoms will normally last 1 or 2 weeks.

In early 1999, we began investigating the use of natural supplements to help ease withdrawal symptoms. Over the past 20 plus years we have continued to improve this approach and our success rate is rather high. With Elavil withdrawal, you should take 4 supplements.

JNK Formula Complete, Neuro Day, Neuro Night and Omega 3 Supreme. You can read How to Start for all chapters of the bestselling book, How to Get Off Psychoactive Drugs Safely, or just follow the instructions on each bottle to know when to take each supplement. Take the supplements for 1 full week before reducing the Elavil and then you can begin your Elavil withdrawal reduction. It really can be this simple.

If you are located in the United States, Canada Click here

What is Elavil

Elavil is a prescription medication used to treat depression and anxiety. It belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). The medication takes some time to build up in the body, which is why it can take a few weeks before people begin noticing a reduction in symptoms of depression or anxiety. If you suddenly stop taking Elavil, however, you may experience symptoms of withdrawal. In the United States this withdrawal is known as Elavil Discontinuation Syndrome but in Europe is known as Elavil Withdrawal.

Antidepressants are among the most prescribed medications in the United States. Of the more than 60 million people who take them in a given month, about one quarter have been taking them for more than 10 years. Often, long-term use is linked to fear of relapse of their symptoms or withdrawal. We have found length of time taking Elavil WILL NOT determine how easy or difficult it will be for you to accomplish a Elavil withdrawal.

People experience symptoms of Elavil withdrawal because of the way SSRI's work in the brain. SSRIs affect the levels of serotonin, a type of mood-regulating neurotransmitter in the brain. When you abruptly stop taking your medication, it doesn't give the brain enough time to adjust to the sudden change. Whether you are stopping Elavil because it is not working for you or you are better and you've decided with your doctor that it makes sense to come off your medication, the quitting process needs to be slow and gradual.

Signs & Symptoms Recent research has found that the severity of SSRI withdrawal is much worse than previously believed. On average, about 46% of people experiencing SSRI withdrawal symptoms describe them as severe. Severe symptoms indicate that withdrawal can potentially interfere with your ability to meet responsibilities at home and at work. It was also found that 10% of the people attempting antidepressant withdrawal, 10% quit the Elavil withdrawal due to a withdrawal side effect known as brain zaps. The Omega 3 Supreme used during Elavil withdrawal is formulated to ease this severe withdrawal side effect.

Most Common Symptoms

The most common symptoms of Elavil withdrawal—occurring in more than one in four people—are as follows:

Dizziness

Muscle tension

Chills

Confusion

Trouble concentrating

Trouble remembering things

Crying

The most common symptoms of Elavil withdrawal are dizziness, muscle tension, and chills, which each affect about 44% of users. Many people also experience confusion and difficulty concentrating. Once again, the supplements have been formulated to help with these symptoms.

Complete Symptoms

The following is a more complete list of symptoms associated with withdrawal:

Temors, muscle tension, restless legs, unsteady gait, or difficulty controlling speech and chewing movements

Nausea, vomiting, cramps, diarrhea, or appetite loss

Headache, muscle pain, weakness, and tiredness.

Dizziness, lightheadedness, difficulty walking

Anxiety, agitation, panic, suicidal ideation, depression, irritability, anger, mania, or mood swings

Nightmares, unusual dreams, excessive/vivid dreams, or insomnia

Brain zaps (like an electrical shock or shiver in your brain), pins and needles, ringing in the ears, strange tastes, or hypersensitivity to sound

Elavil withdrawal can take a real toll on your life, both physically and emotionally. Antidepressants like Elavil work by increasing serotonin levels in your brain. When you stop taking them, it takes your brain a while to get used to the drug’s absence. Unfortunately, the amount of time this takes can vary widely. Elavil withdrawal symptoms typically arrive one to three days after your last dose. It can start sooner (within hours) or later (more than a week). This is why most inpatient facilities fail with Elavil withdrawal. Insurance may pay only 9 days of treatment and by the time you are off the plane near your city, Elavil withdrawal is back and in full effect. Elavil withdrawal should never be rushed.

Coping & Relief

The best way to find relief from Elavil withdrawal is to use the supplements mentioned above, reduce the Elavil gradually and only continue to reduce when you are feeling very well. If you are still experiencing symptoms of depression, definitely send us an e-mail and we will help you adjust supplements and assist you in finding the cause.

Taper Off Medication Slowly In 1999, our founder, Jim Harper, published a guideline for reducing medications. That guideline has been adapted to all psychoactive medications by the drug manufacturers. The most effective way to minimize symptoms of withdrawal is to slowly taper off your medication. “Reduce the medication slowly. If withdrawal symptoms begin go back up to the last dosage you were doing fine at, stay at that dosage until all withdrawal has subsided. When you continue with withdrawal reduce the medication slower than the previous reductions.

”Elavil should only be reduced by 10%. Some people will need to reduce the Elavil by 5%.Reductions of the Elavil can be made every 7 days or in some cases every 14 days. Slow and steady wins this race.

Tapering involves adjusting your dose by a small amount, gradually decreasing until your body gets used to lower levels of the medication. Talk to your doctor who can then create a dose schedule and carefully monitor the process to avoid severe symptoms.

Practice Good Self-Care

Taking good care of your health as you stop taking Elavil can also help you to better manage any withdrawal symptoms that you experience. Some steps you can take that might help you cope with withdrawal symptoms include:

Do not change your diet when tapering. This can alter metabolism rater of the Elavil and create a withdrawal symptom

Follow your doctor's taping recommendations

Get plenty of rest

Get regular mild exercise

Get support from family, friends, or support groups

If you or someone you love shows any of the following signs or symptoms after stopping or during a Elavil taper, get help: Becoming preoccupied with death, dying, or violence

Engaging in risky or self-destructive activities, such as driving drunk

Feeling hopeless or trapped

Gathering the means to commit suicide, such as bullets or pills

Getting affairs in order or giving away belongings

Having intense mood swings

Planning how you would commit suicide if you were going to do it

Saying goodbye to people as if it were the last time Talking or thinking about suicide more than normal, for example, “I wish I were dead”

1. Nelson JC MD, Spyker DA PhD MD “Morbidity and Mortality Associated With Medications Used in the Treatment of Depression: An Analysis of Cases Reported to U.S. Poison Control Centers, 2000–2014” American Journal of Psychiatry, [INTERNET] 2017 Jan 31 [cited 2022 May 19]

2. Umaharan T, Sivayokan S, Sivansuthan S. Amitriptyline Dependence and Its Associations: A Case Report and Literature ReviewCase Rep Psychiatry. 2021;2021:6647952. Published 2021 Jan 29. doi:10.1155/2021/6647952 [cited 2022 May 19]

3. Davison P, Wardrope J. Acute amitriptyline withdrawal and hyponatraemia. A case report. Drug Saf. 1993 Jan;8(1):78-80. doi: 10.2165/00002018-199308010-00009. PMID: 8471189. [cited 2022 May 19]

4. Rusconi AC, Carlone C, Muscillo M, Coccanari de’ Fornari MA, Podda L, Piccione M. Sindrome da sospensione di SSRI: incidenza e differenze su tre gruppi di pazienti in trattamento con paroxetina [SSRI discontinuation syndrome: incidence and differences on three groups of patients treated with paroxetine]. Riv Psichiatr. 2009 May-Jun;44(3):169-75. Italian. PMID: 20066803. [cited 2022 May 19]

5. Dunsaed F, et al., “Standardised detoxification in cases of polydrug use.” N.D. Tidsskriftet [online] [cited 2022 May 19]

6. Robertson W, “Symptoms of tricyclic antidepressants.” CMA Journal [Sept 1 1981] [cited 2022 May 19]

7. Wolfe RM. Antidepressant withdrawal reactions. Am Fam Physician. 1997 Aug;56(2):455-62. Erratum in: Am Fam Physic. 1998 Feb 15;57(4):646. PMID: 9262526. [cited 2022 May 19]

8. Sahay M, Sahay R. Hyponatremia: A practical approachIndian J Endocrinol Metab. 2014;18(6):760-771. doi:10.4103/2230-8210.141320 [cited 2022 May 19]

9. FDA label Amitriptyline HCI [online] [cited 2022 May 19]

10. Dilsaver SC, Greden JF. Antidepressant withdrawal phenomena. Biol Psychiatry. 1984 Feb;19(2):237-56. PMID: 6324897. [cited 2022 May 19]

11. Lejoyeux M, Adès J. Antidepressant discontinuation: a review of the literature. J Clin Psychiatry. 1997;58 Suppl 7:11-5; discussion 16. PMID: 9219488. [cited 2022 May 19]

12. Lenzer J. Frank Joseph AydBMJ. 2008;336(7654):1196. doi:10.1136/bmj.a131 [cited 2022 May 19]

13. Thour A, Marwaha R. Amitriptyline. [Updated 2020 Nov 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537225/ [cited 2022 May 19]

14. Chen LW, Chen MY, Lian ZP, et al. Amitriptyline and Sexual Function: A Systematic Review Updated for Sexual Health PracticeAm J Mens Health. 2018;12(2):370-379. doi:10.1177/1557988317734519 [cited 2022 May 19]

15. Couper-Smartt JD, Rodham R. A technique for surveying side-effects of tricyclic drugs with reference to reported sexual effects. J Int Med Res. 1973;1(5):473-6. doi: 10.1177/030006057300100541. PMID: 4806734. [cited 2022 May 19]

16. Cowen PJ, Braddock LE, Gosden B. The effect of amitriptyline treatment on the growth hormone response to apomorphine. Psychopharmacology (Berl). 1984;83(4):378-9. doi: 10.1007/BF00428550. PMID: 6436869. [cited 2022 May 19]

17. Gillman PK. Tricyclic antidepressant pharmacology and therapeutic drug interactions updated. Br J Pharmacol. 2007;151(6):737-748. doi:10.1038/sj.bjp.0707253 [cited 2022 May 19]

18. Haider S, Grabovac I, Rieder A, Dorner TE. Depressive Symptoms, Lack of Physical Activity, and Their Combination Towards Health Care Utilisation Frequency. Int J Environ Res Public Health. 2019 Nov 26;16(23):4697. doi: 10.3390/ijerph16234697. PMID: 31779075; PMCID: PMC6926940. [cited 2022 May 19]

19. Ljungberg T, Bondza E, Lethin C. Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and DepressionInt J Environ Res Public Health. 2020;17(5):1616. Published 2020 Mar 2. doi:10.3390/ijerph17051616 [cited 2022 April 28]

20. Ruusunen A, Lehto SM, Mursu J, Tolmunen T, Tuomainen TP, Kauhanen J, Voutilainen S. Dietary patterns are associated with the prevalence of elevated depressive symptoms and the risk of getting a hospital discharge diagnosis of depression in middle-aged or older Finnish men. J Affect Disord. 2014 Apr;159:1-6. doi: 10.1016/j.jad.2014.01.020. Epub 2014 Feb 14. PMID: 24679382. [cited 2022 May 19]

21. Huddy RL, Torres SJ, Milte CM, McNaughton SA, Teychenne M, Campbell KJ. Higher Adherence to the Australian Dietary Guidelines Is Associated with Better Mental Health Status among Australian Adult First-Time Mothers. J Acad Nutr Diet. 2016 Sep;116(9):1406-1412. doi: 10.1016/j.jand.2016.01.010. Epub 2016 Mar 4. PMID: 26947337. [cited 2022 May 19]

22. Moraczewski J, Aedma KK. Tricyclic Antidepressants. [Updated 2020 Dec 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557791/[cited 2022 May 19]>

23. Henssler J, Heinz A, Brandt L, Bschor T. Antidepressant Withdrawal and Rebound Phenomena. Dtsch Arztebl Int. 2019 May 17;116(20):355-361. doi: 10.3238/arztebl.2019.0355. PMID: 31288917; PMCID: PMC6637660. [cited 2022 May 19]

24. Smith JC, Curry SC. Prolonged toxicity after amitriptyline overdose in a patient deficient in CYP2D6 activityJ Med Toxicol. 2011;7(3):220-223. doi:10.1007/s13181-011-0158-2 [cited 2022 May 19]

25. Medlineplus.gov Fact Sheet “Amitriptyline” [online] [cited 2022 May 19]

26. Mischoulon, D. (2008). Natural Medications for Psychiatric Disorders: Considering the Alternatives. Argentina: Lippincott Williams & Wilkins. [cited 2022 May 19]

27. Uhr M, Grauer MT, Yassouridis A, Ebinger M. Blood-brain barrier penetration and pharmacokinetics of amitriptyline and its metabolites in p-glycoprotein (abcb1ab) knock-out mice and controls. J Psychiatr Res. 2007 Jan-Feb;41(1-2):179-88. doi: 10.1016/j.jpsychires.2005.10.005. Epub 2006 Jan 4. PMID: 16387324. [cited 2022 May 19]

28. Cipolla MJ. The adaptation of the cerebral circulation to pregnancy: mechanisms and consequences. J Cereb Blood Flow Metab. 2013 Apr;33(4):465-78. doi: 10.1038/jcbfm.2012.210. Epub 2013 Jan 16. PMID: 23321787; PMCID: PMC3618397. [cited 2022 May 19]

29. Bérard A, Zhao J, Sheehy O, Antidepressant use during pregnancy and the risk of major congenital malformations in a cohort of depressed pregnant women: an updated analysis of the Quebec Pregnancy Cohort BMJ Open 2017;7:e013372. doi: 10.1136/bmjopen-2016-013372 [cited 2022 May 19]

30. Stewart JM, Clarke D. “He’s dizzy when he stands up”: an introduction to initial orthostatic hypotensionJ Pediatr. 2011;158(3):499-504. doi:10.1016/j.jpeds.2010.09.004 [cited 2022 May 19]

31. Rondon H, Badireddy M. Hyponatremia. [Updated 2022 Jan 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470386/ [cited 2022 May 19]

32. Hofmann SG, Asnaani A, Vonk IJ, Sawyer AT, Fang A. The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses. Cognit Ther Res. 2012 Oct 1;36(5):427-440. doi: 10.1007/s10608-012-9476-1. Epub 2012 Jul 31. PMID: 23459093; PMCID: PMC3584580. [cited 2022 May 19]

33. WHO Model List of Essential Medicines [pdf online] [cited May 19]

34. Papp A, Onton JA. Brain Zaps: An Underappreciated Symptom of Antidepressant Discontinuation. Prim Care Companion CNS Disord. 2018 Dec 20;20(6):18m02311. doi: 10.4088/PCC.18m02311. PMID: 30605268. [cited 2023 July 29]