Trintellix Vortioxetine Side Effects
Nausea: Nausea is a common side effect of Trintellix, occurring in up to 21% of patients. It may be mild or severe and may be accompanied by vomiting, loss of appetite, or stomach discomfort.Diarrhea: Diarrhea is another common side effect of Trintellix, occurring in up to 8% of patients. It may be mild or severe and may be accompanied by stomach cramps, bloating, or dehydration.
Dizziness: Dizziness is a common side effect of Trintellix, occurring in up to 7% of patients. It may be mild or severe and may be accompanied by lightheadedness, vertigo, or fainting.
Dry mouth: Dry mouth is a common side effect of Trintellix, occurring in up to 7% of patients. It may be mild or severe and may be accompanied by a dry, sticky feeling in the mouth, difficulty swallowing, or bad breath.
Constipation: Constipation is a common side effect of Trintellix, occurring in up to 6% of patients. It may be mild or severe and may be accompanied by abdominal pain, bloating, or difficulty passing stool.
Vomiting: Vomiting is a common side effect of Trintellix, occurring in up to 6% of patients. It may be mild or severe and may be accompanied by nausea, loss of appetite, or dehydration.
Insomnia: Insomnia is a common side effect of Trintellix, occurring in up to 6% of patients. It may be mild or severe and may be accompanied by difficulty falling or staying asleep, restless sleep, or nightmares.
Sexual dysfunction: Sexual dysfunction is a common side effect of Trintellix, occurring in up to 5% of patients. It may include decreased libido, difficulty achieving or maintaining an erection or orgasm, or decreased sexual satisfaction.
Headache: Headache is a common side effect of Trintellix, occurring in up to 5% of patients. It may be mild or severe and may be accompanied by nausea, sensitivity to light or sound, or muscle tension.
Abdominal pain: Abdominal pain is a common side effect of Trintellix, occurring in up to 5% of patients. It may be mild or severe and may be accompanied by bloating, nausea, or diarrhea.
Fatigue: Fatigue is a common side effect of Trintellix, occurring in up to 5% of patients. It may be mild or severe and may be accompanied by weakness, lethargy, or difficulty concentrating.
Increased sweating: Increased sweating is a common side effect of Trintellix, occurring in up to 5% of patients. It may be mild or severe and may be accompanied by clamminess, skin irritation, or body odor.
Weight changes: Weight changes are a common side effect of Trintellix, occurring in up to 5% of patients. They may include weight gain or weight loss and may be accompanied by changes in appetite or metabolism.
Anxiety: Anxiety is a less common side effect of Trintellix, occurring in up to 4% of patients. It may be mild or severe and may be accompanied by nervousness, restlessness, or a sense of impending doom.
Insomnia: Insomnia is a less common side effect of Trintellix, occurring in up to 3% of patients. It may be mild or severe and may be accompanied by difficulty falling or staying asleep, restless sleep, or nightmares.
Suicidal thoughts or behavior: Suicidal thoughts or behavior is a less common but serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by feelings of hopelessness, worthlessness, or helplessness, as well as changes in mood or behavior.
Serotonin syndrome: Serotonin syndrome is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by agitation, confusion, rapid heart rate, muscle rigidity, and high fever.
Hyponatremia: Hyponatremia is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by headache, confusion, seizures, and even coma in severe cases.
Bleeding events: Bleeding events are a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. They may include unusual bleeding or bruising, nosebleeds, or blood in the stool or urine.
Tardive dyskinesia: Tardive dyskinesia is a rare but potentially permanent side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by involuntary muscle movements, particularly in the face and tongue.
Allergic reactions: Allergic reactions are a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. They may include rash, hives, itching, swelling of the face or throat, difficulty breathing, and dizziness.
Photosensitivity: Photosensitivity is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by skin rash, redness, or blistering after exposure to sunlight or UV light.
Confusion: Confusion is a less common side effect of Trintellix, occurring in up to 2% of patients. It may be mild or severe and may be accompanied by memory problems, disorientation, or difficulty concentrating.
Hallucinations: Hallucinations are a less common side effect of Trintellix, occurring in up to 2% of patients. They may be auditory or visual and may be accompanied by delusions, paranoia, or disorganized thinking.
Seizures: Seizures are a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. They may be accompanied by loss of consciousness, muscle spasms, or confusion.
Hypertension: Hypertension is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by headache, dizziness, or chest pain.
Orthostatic hypotension: Orthostatic hypotension is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by dizziness, lightheadedness, or fainting upon standing up.
Rash: Rash is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be mild or severe and may be accompanied by itching, redness, or blisters.
Stevens-Johnson syndrome: Stevens-Johnson syndrome is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by fever, skin rash, and blistering of the mucous membranes.
Hepatitis: Hepatitis is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by jaundice, nausea, vomiting, or abdominal pain.
Renal failure: Renal failure is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by decreased urine output, swelling of the feet or ankles, or confusion.
Akathisia: Akathisia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by restlessness, agitation, or a sense of internal discomfort.
Bruxism: Bruxism is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by grinding or clenching of the teeth, particularly during sleep.
Hypomania/mania: Hypomania/mania is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by elevated mood, increased energy, or reckless behavior.
Photosensitivity: Photosensitivity is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by skin rash, redness, or blistering after exposure to sunlight or UV light.
Dysgeusia: Dysgeusia is a rare but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by changes in taste perception or a metallic taste in the mouth.
Paraesthesia: Paraesthesia is a rare but potentially bothersome side effect of Trintellix, occurring in less 1% of patients.
Restless leg syndrome: Restless leg syndrome is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by an uncomfortable sensation in the legs that is relieved by movement.
Akinesia: Akinesia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by decreased voluntary movement, muscle rigidity, or tremors.
Apathy: Apathy is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by a lack of interest or motivation, decreased emotional responsiveness, or social withdrawal.
Ataxia: Ataxia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by unsteady gait, loss of balance, or difficulty coordinating movements.
Chills: Chills are a less common side effect of Trintellix, occurring in up to 1% of patients. They may be accompanied by fever, shivering, or muscle aches.
Depersonalization: Depersonalization is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a sense of detachment from oneself or one's surroundings, feelings of unreality, or altered perception of time.
Euphoria: Euphoria is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by feelings of extreme happiness, elation, or excitement.
Excessive thirst: Excessive thirst is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by dry mouth, dehydration, or frequent urination.
Facial edema: Facial edema is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by swelling of the face, lips, or tongue, difficulty breathing or swallowing, or hives.
Flatulence: Flatulence is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by bloating, abdominal pain, or discomfort.
Gastrointestinal hemorrhage: Gastrointestinal hemorrhage is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by vomiting blood, bloody or black stools, or abdominal pain.
Hematoma: Hematoma is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by swelling, discoloration, or tenderness at the site of injury.
Hypotension: Hypotension is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by dizziness, lightheadedness, or fainting.
Impulsivity: Impulsivity is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by risky or impulsive behavior, difficulty controlling impulses, or poor decision-making.
Increased appetite: Increased appetite is a less common side effect of Trintellix, occurring in up to 1% of patients.
Mood swings: Mood swings are a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. They may be accompanied by sudden or intense changes in mood, including irritability, anger, or aggression.
Myoclonus: Myoclonus is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by sudden, involuntary muscle twitches or jerks.
Oropharyngeal pain: Oropharyngeal pain is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by pain or discomfort in the throat, mouth, or tongue.
Palpitations: Palpitations are a less common side effect of Trintellix, occurring in up to 1% of patients. They may be accompanied by a rapid or irregular heartbeat, chest pain, or shortness of breath.
Paresthesia: Paresthesia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by abnormal sensations, such as tingling, numbness, or burning, in various parts of the body.
Peripheral edema: Peripheral edema is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by swelling of the feet or ankles, difficulty walking, or skin changes.
Pruritus: Pruritus is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by itching, rash, or skin irritation.
Pyrexia: Pyrexia is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by fever, chills, or sweating.
Rhabdomyolysis: Rhabdomyolysis is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by muscle pain, weakness, or dark urine.
Severe skin reactions: Severe skin reactions are a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. They may include Stevens-Johnson syndrome, toxic epidermal necrolysis, or drug reaction with eosinophilia and systemic symptoms.
Speech disorder: Speech disorder is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by difficulty speaking or articulating words, slurred speech, or stuttering.
Supraventricular tachycardia: Supraventricular tachycardia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a rapid or irregular heartbeat, shortness of breath, or chest pain.
Syncope: Syncope is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by loss of consciousness, dizziness, or lightheadedness.
Tremor: Tremor is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by shaking or quivering of the limbs, head.
Urticaria: Urticaria is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by hives or welts on the skin, itching, or redness.
Urinary retention: Urinary retention is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by difficulty urinating, a weak urine stream, or a sense of incomplete emptying of the bladder.
Vertigo: Vertigo is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a sense of spinning or dizziness, nausea, or vomiting.
Visual disturbances: Visual disturbances are a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. They may include blurred vision, double vision, or changes in color perception.
Voice alteration: Voice alteration is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by changes in pitch, tone, or volume of the voice, or hoarseness.
Weight gain: Weight gain is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by increased appetite, changes in metabolism, or decreased physical activity.
Weight loss: Weight loss is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by decreased appetite, changes in metabolism, or increased physical activity.
Abnormal dreams: Abnormal dreams are a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. They may be accompanied by vivid or unusual dream content, nightmares, or sleep disturbances.
Agitation: Agitation is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by restlessness, anxiety, or irritability.
Alopecia: Alopecia is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by hair loss or thinning, particularly on the scalp.
Anaphylaxis: Anaphylaxis is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by hives, swelling of the face or throat, difficulty breathing, or rapid heartbeat.
Asthenia: Asthenia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by weakness, fatigue, or lack of energy.
Breast enlargement: Breast enlargement is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by tenderness, soreness, or discomfort.
Cardiac arrhythmia: Cardiac arrhythmia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by irregular heartbeat, palpitations, or fainting.
Chest discomfort: Chest discomfort is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by chest pain, pressure.
Coordination abnormal: Coordination abnormal is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by difficulty with fine motor skills, such as writing or buttoning clothing, or difficulty with gross motor skills, such as walking or running.
Delirium: Delirium is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by confusion, disorientation, or changes in consciousness.
Dysarthria: Dysarthria is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by difficulty with speech, such as slurred speech, difficulty pronouncing words, or difficulty controlling the pitch or volume of the voice.
Dyskinesia: Dyskinesia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by involuntary movements, such as twitching, jerking, or writhing.
Dyspnea: Dyspnea is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by shortness of breath, difficulty breathing, or a feeling of suffocation.
Electrocardiogram QT prolonged: Electrocardiogram QT prolonged is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by changes in the electrical activity of the heart, which can lead to abnormal heart rhythms.
Eosinophilia: Eosinophilia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by an increase in the number of eosinophils, a type of white blood cell, in the blood.
Eye pain: Eye pain is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by discomfort, itching, redness, or sensitivity to light.
Hyperglycemia: Hyperglycemia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by high blood sugar levels, which can lead to complications such as diabetic ketoacidosis or hyperosmolar hyperglycemic state.
Hyperkinesia: Hyperkinesia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by excessive or abnormal movements, such as fidgeting, tapping, or pacing.
Hypersensitivity: Hypersensitivity is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by an allergic reaction, which can lead to symptoms such as rash, hives, or difficulty breathing.
Hyponatremia: Hyponatremia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by low sodium levels in the blood, which can lead to symptoms such as confusion, seizures, or coma.
Hypotension: Hypotension is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by low blood pressure, which can lead to symptoms such as dizziness, fainting, or lightheadedness.
Hypoventilation: Hypoventilation is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by shallow breathing or a decreased rate of breathing.
Hypoxia: Hypoxia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a decrease in the oxygen supply to the body's tissues, which can lead to symptoms such as shortness of breath, rapid heartbeat, or confusion.
Increased appetite: Increased appetite is a less common side effect of Trintellix, occurring in up to 1% of patients. It may be accompanied by weight gain or changes in metabolism.
Insomnia: Insomnia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by difficulty falling asleep or staying asleep, early morning awakening, or poor quality sleep.
Kidney failure: Kidney failure is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a decrease in kidney function, which can lead to symptoms such as swelling, fatigue, or shortness of breath.
Liver failure: Liver failure is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a decrease in liver function, which can lead to symptoms such as jaundice, abdominal pain, or confusion.
Mania: Mania is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by episodes of elevated or irritable mood, increased energy, racing thoughts, or risky behavior.
Nephritis: Nephritis is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by inflammation of the kidneys, which can lead to symptoms such as fever, blood in the urine, or high blood pressure.
Neutropenia: Neutropenia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a decrease in the number of neutrophils, a type of white blood cell, in the blood.
Pancreatitis: Pancreatitis is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by inflammation of the pancreas, which can lead to symptoms such as abdominal pain, nausea, or vomiting.
Photosensitivity: Photosensitivity is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by an increased sensitivity to sunlight, which can lead to skin reactions such as rash or redness.
Psychotic disorder: Psychotic disorder is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by delusions, hallucinations, or disordered thinking.
Renal impairment: Renal impairment is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a decrease in kidney function, which can lead to symptoms such as swelling, fatigue, or shortness of breath.
Rhabdomyolysis: Rhabdomyolysis is a rare but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by breakdown of muscle tissue, which can lead to symptoms such as muscle pain, weakness, or dark urine.
Seizure: Seizure is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by abnormal electrical activity in the brain, which can lead to symptoms such as convulsions, loss of consciousness, or muscle spasms.
Serotonin syndrome: Serotonin syndrome is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by an excess of serotonin in the brain, which can lead to symptoms such as agitation, confusion, fever, rapid heartbeat, or muscle rigidity.
Stevens-Johnson syndrome: Stevens-Johnson syndrome is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a severe skin reaction, which can lead to symptoms such as blistering, peeling, or sores.
Suicidal ideation: Suicidal ideation is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by thoughts of self-harm, suicidal thoughts, or suicide attempts.
Thrombocytopenia: Thrombocytopenia is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a decrease in the number of platelets, a type of blood cell that helps with clotting, in the blood.
Tinnitus: Tinnitus is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by ringing, buzzing, or other sounds in the ears.
Torsade de pointes: Torsade de pointes is a rare but potentially life-threatening side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by abnormal heart rhythms, which can lead to symptoms such as dizziness, fainting, or sudden cardiac arrest.
Tremor: Tremor is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by involuntary shaking or trembling, particularly in the hands, arms, or legs.
Urinary incontinence: Urinary incontinence is a less common but potentially bothersome side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by a loss of bladder control, which can lead to involuntary leakage of urine.
Withdrawal syndrome: Withdrawal syndrome is a less common but potentially serious side effect of Trintellix, occurring in less than 1% of patients. It may be accompanied by symptoms such as dizziness, nausea, headache, or irritability, when the medication is stopped abruptly or the dose is rapidly decreased.